Losing a race is unusual for the crypto industry’s political action committee, Fairshake, which has recorded a dominant record in the past two congressional elections. But the Illinois primaries this week saw its biggest-ever setback, likely to conclude with a new member of the Senate next year being somebody the PAC spent more than $10 million trying to defeat.

Illinois Lt. Gov. Juliana Stratton won her Democratic primary, and her state’s Democrat lean means she’s likely to be its next senator after the November general election. One of Fairshake’s affiliates had devoted millions to purchase opposition advertising in that race and to support two of her opponents — representing more than 5% of the funds it’s said it had on-hand this…