Making A PCR Machine Crypto Sign Its Results

Money, status, or even survival – there’s no shortage of incentives for faking results in the scientific community. What can we do to prevent it, or at least make it noticeable? One possible solution is cryptographic signing of measurement results.

Here’s a proof-of-concept from [Clement Heyd] and [Arbion Halili]. They took a ThermoFisher Scientific 7500 Fast PCR (Polymerase Chain Reaction) machine, isolated its daughter-software, and confined it into a pipeline that automatically signs each result with help of a HSM (Hardware Security Module).

A many machines do, this one has to be paired to a PC, running bespoke software. This one’s running Windows XP, at least! The software got shoved into a heavily…

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